THE EFFICACY AND SAFETY OF ICOTINIB IN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER PREVIOUSLY TREATED WITH CHEMOTHERAPY: A SINGLE-ARM, MULTI-CENTER, PROSPECTIVE STUDY.

Icotinib is a small molecule targeting epidermal growth factor receptor tyrosine kinase, which shows non-inferior efficacy and better safety comparing to gefitinib in previous phase III trial.The present study was designed to further evaluate the efficacy and safety of icotinib in patients with advanced non-small-cell lung cancer (NSCLC) previously

The relations between Russia and the papal state in the first years of the Northern war are analyzed.Describes the background to the trip B.I.Kurakin in Rome in 1707, gives a brief overview of the contacts of the Russian state with the States of the Apennine Peninsula at the turn of XVII - XVIII centuries.The personal qualities of the first Russian

Abstract Studies indicate EGFL7 as an important gene in controlling angiogenesis and cancer growth, including in colorectal cancer (CRC).Anti-EGFL7 agents are being explored, yet without promising results.Therefore, the role of EGFL7 in CRC carcinogenesis should be investigated.This study aimed to evaluate the prognostic value of EGFL7 Lighting Acc